Oxygen in stem cell biology: a critical component of the stem cell niche.

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The defining hallmark of stem cells is their means to self-renew and keep multipotency. This capability is determined by the stability of advanced alerts in their microenvironment.

Low oxygen tensions (hypoxia) keep undifferentiated states of embryonic, hematopoietic, mesenchymal, and neural stem cell phenotypes and in addition affect proliferation and cell-fate dedication.

Recent proof has recognized a broader spectrum of stem cells influenced by hypoxia that features most cancers stem cells and induced pluripotent stem cells. These findings have essential implications on our understanding of growth, illness, and tissue-engineering practices and moreover elucidate an added dimension of stem cell management inside the area of interest.

 

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Antinuclear antibodies: diagnostic markers for autoimmune ailments and probes for cell biology.

  • Cancers initially develop from regular cells that achieve the means to proliferate aberrantly and ultimately flip malignant. These cancerous cells then develop clonally into tumors and ultimately have the potential to metastasize.

GOAT ANTI HUMAN TNF ALPHA

MBS221500-01mg 0.1mg
EUR 660

GOAT ANTI HUMAN TNF ALPHA

MBS221500-5x01mg 5x0.1mg
EUR 2795

Tumor necrosis factor alpha TNF-? (72 - 82), human (AA: Pro-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg) (MW: 1171.33)

SP-86635-5 5 mg
EUR 343.2

MOUSE ANTI HUMAN TNF ALPHA

MBS213142-05mg 0.5mg
EUR 1165

MOUSE ANTI HUMAN TNF ALPHA

MBS213142-5x05mg 5x0.5mg
EUR 5080

MOUSE ANTI HUMAN TNF ALPHA

MBS213345-02mg 0.2mg
EUR 935

MOUSE ANTI HUMAN TNF ALPHA

MBS213345-5x02mg 5x0.2mg
EUR 4045

Monoclonal Anti-Human Tumor Necrosis Factor-Alpha (TNF-alpha) IgG #1 aff. Pure

TNFA11-M 100 ug
EUR 578.4

Monoclonal Anti-Human Tumor Necrosis Factor-Alpha (TNF-alpha) IgG #2, aff. Pure

TNFA12-M 100 ug
EUR 578.4

Alpha 2-Antiplasmin, Human Plasma

A2AP15-100 100 ug
EUR 196.8

Alpha 1-Antitrypsin, Human Plasma

A1AT15-N 1 mg
EUR 196.8

Recombinant (E.Coli) Human p38 alpha/SAPK2 alpha

RP-675 1 ug
EUR 343.2

Rabbit Anti-Rat TNF-alpha Converting Enzyme (TACE) antiserum

TACE11-S 100 ul
EUR 548.4

Alpha 1-Antichymotrypsin , Human Plasma

A1CT15-N-100 100 ug
EUR 196.8

Rabbit Anti-Human alpha-Tubulin IgG

TUBA13-A 100 ul
EUR 578.4

Goat Anti-Human Tumor Necrosis Factor-Alpha (TNF-alpha) IgG #2, aff. Pure (neutralzing)

TNFA13-A 100 ul
EUR 578.4

Pig Tumor Necrosis Factor Alpha (TNF-a) ELISA Kit, 96 tests, Quantitative

9965 1 Kit
EUR 927.6

Recombinant (E.Coli) purified human Tumor Necrosis Factor-Alpha (TNF-alpha), biologically active

TNFA15-R-10 10 ug
EUR 270

Monoclonal Anti-Human alpha-Tubulin IgG

TUBA12-M 100 ul
EUR 578.4

Rabbit Anti-human Topoisomerase II alpha (TOP2 alpha) IgG, aff pure

TOP2A11-A 100 ug
EUR 578.4

Canine Tumor Necrosis Factor alpha (TNF-a) ELISA Kit, 96 tests, Quantitative

10460 1 Kit
EUR 927.6

Bovine Tumor necrosis factor alpha (TNF-A) ELISA Kit, 96 tests, Quantitative

9810 1 Kit
EUR 927.6

Chicken Anti-Human alpha 1 anti-trypsin IgG/Y

A1AT12-A 100 ul
EUR 578.4

Tumor necrosis factor alpha TNF-? (78-96) (human) (AA: His-Thr-Ile-Ser-Arg-Ile-Ala-Val-Ser-Tyr-Gln-Thr-Lys-Val-Asn-Leu-Leu-Ser-Ala) (MW: 2101.45)

SP-89730-1 1 mg
EUR 196.8

Rabbit Anti-Human p73 alpha antiserum # 2

P73A12-S 100 ul
EUR 548.4

Tumor necrosis factor alpha TNF-? (46-65) (human) (AA: Asn-Gln-Leu-Val-Val-Pro-Ser-Glu-Gly-Leu-Tyr-Leu-Ile-Tyr-Ser-Gln-Val-Leu-Phe-Lys) (MW: 2310.74)

SP-89728-1 1 mg
EUR 489.6

Rabbit Anti-Human Glutathione Transferase alpha (GST-alpha) antiserum

GSTA12-S 100 ul
EUR 548.4

Guinea pig Tumor Necrosis Factor Alpha (TNF-a) ELISA Kit, 96 tests, Quantitative

9870 1 Kit
EUR 927.6

Tumor necrosis factor alpha TNF-? (31 - 45), human (AA: Arg-Arg-Ala-Asn-Ala-Leu-Leu-Ala-Asn-Gly-Val-Glu-Leu-Arg-Asp) (MW: 1667.90)

SP-86636-1 1 mg
EUR 196.8

Human Alpha-Thrombin (human plasma), purified

TBNA16-N-100 100 ug
EUR 196.8

human Topoisomerase II alpha (TOP2 alpha) Control/blocking peptide

TOP2A11-P 100 ug
EUR 196.8

Recombinant Human Alpha-Synuclein

RP-847 20 ug
EUR 196.8

Rabbit Anti-Human Estrogen receptor alpha (ER-alpha) peptide IgG

ERA12-A 100 ug
EUR 578.4

Rabbit Anti-Human p73 alpha/beta antiserum # 1

P73A11-S 100 ul
EUR 548.4

Recombinant purified human TNF Receptor 2 (TNFR2/TNF-RII, Etannercept/TNF-R75, p75TNFR) protein (E.Coli, His-tag)

TNFR25-R-20 10 ug
EUR 343.2

Recombinant purified, human Interleukin-1 alpha (IL-1 alpha), active

IL1A15-R-10 10 ug
EUR 416.4

Monoclonal anti-human Alpha (FSH-Alpha), IgG clone 3 aff pure

FSHA12-M 1 mg
EUR 578.4

Goat Anti-human Alpha fetoprotein (AFP) IgG, pure

AFP13-A 1 mg
EUR 781.2

Goat Anti-Human Lutenizing Hormone Alpha (LH-Alpha) IgG aff pure

LHA13-A 1 mg
EUR 343.2

Rabbit Anti-Rat TNF-alpha Converting Enzyme (TACE), IgG aff. Pure

TACE11-A 100 ug
EUR 578.4

Goat Anti-human Chorionic Gonadotropin Alpha (hCG-Alpha) IgG aff pure

HCGA13-A 1 mg
EUR 343.2

Tumor necrosis factor alpha TNF-? (10-36) (human) (AA: Asp-Lys-Pro-Val-Ala-His-Val-Val-Ala-Asn-Pro-Gln-Ala-Glu-Gly-Gln-Leu-Gln-Trp-Leu-Asn-Arg-Arg-Ala-Asn-Ala-Leu) (MW: 2996.41)

SP-89727-1 1 mg
EUR 270

Rabbit Anti-Human HE2 alpha IgG #1, aff pure

HE2A11-A 100 ug
EUR 578.4

Rabbit Anti-Human p73 alpha/ IgG # 2, aff pure

P73A12-A 100 ug
EUR 578.4

Rabbit Anti-Human alpha-Tubulin IgG-HRP Conjugate

TUBA13-HRP 100 ul
EUR 518.4

Recombinant (E.Coli) Human Thyrostimulin Alpha

RP-595 10 ug
EUR 343.2

Rabbit Anti-Human alpha-Tubulin IgG-Biotin Conjugate

TUBA13-BTN 100 ul
EUR 562.8

Alpha 1-Antitrypsin (A1AT), Human protein control for WB

A1AT11-C 100 ul
EUR 343.2

Alpha 2-HS Glycoprotein, Human Plasma

A2HG15-N 1 mg
EUR 343.2

Goat Anti-Human Alpha 1-Antitrypsin (A1AT) IgG, unlabeled

A1AT11-A 100 ul
EUR 489.6

Alpha 2-Macroglobulin (A2M), Human Plasma

A2MG15-N 1 mg
EUR 196.8

Rabbit Anti-Human Resistin-Like protein alpha (RELM-alpha/FIZZ1) antiserum #2

RELMA12-S 100 ul
EUR 548.4

Chicken Anti-Human Alpha 2 Macroglobulin (A2M) IgG/Y

A2MG13-A 100 ul
EUR 578.4

Recombinant (E.Coli) Human Crystallin Alpha A

RP-611 20 ug
EUR 196.8

Recombinant (E.Coli) Human Crystallin Alpha B

RP-612 20 ug
EUR 196.8

Human Alpha Feto Protein (AFP) High Pure

AFP15-N 1 mg
EUR 854.4

Monoclonal Anti-Human Chorionic Gonadotropin Alpha (hCG-alpha) IgG #1, aff pure

HCGA11-M 1 mg
EUR 343.2

Rabbit Anti-Human p73 alpha/beta IgG # 1, aff pure

P73A11-A 100 ug
EUR 578.4

Monoclonal Anti-human Chronionic Gonadotropin Alpha (hCG-Alpha) IgG #2, caff pure

HCGA12-M 1 mg
EUR 343.2

Mouse Monoclonal Anti-human Alpha fetoprotein (AFP) (clone 1)

AFP11-M 1 mg
EUR 578.4

Mouse Monoclonal Anti-human Alpha fetoprotein (AFP) (clone 2)

AFP12-M 1 mg
EUR 578.4

HUMAN ANTI TNF ALPHA (INFLIXIMAB BIOSIMILAR)

MBS226034-02mg 0.2mg
EUR 715

HUMAN ANTI TNF ALPHA (INFLIXIMAB BIOSIMILAR)

MBS226034-5x02mg 5x0.2mg
EUR 3045

Rabbit Anti-Human Alpha Defensin 4 (NP-4) antiserum #1

HDEFA41-S 100 ul
EUR 548.4

Rabbit Anti-Human Alpha Defensin 5 (NP-5),antiserum #1

HDEFA51-S 100 ul
EUR 548.4

Rabbit Anti-Human Alpha Defensin 6 (NP-6) antiserum #1

HDEFA61-S 100 ul
EUR 548.4

Human Alpha Synuclein (A30P) Recombinant protein

SYN-A30P-R 50ug
EUR 315.6

Human Alpha Synuclein (A53T) Recombinant protein

SYN-A53T-R 50ug
EUR 315.6

Recombinant (E.Coli) Human Estrogen Receptor Alpha

RP-940 2 ug
EUR 416.4

Anti-Human TNF alpha

GWB-619378 1 mg Ask for price

Anti-Human TNF-&alpha

GWB-BIG93C 500ug Ask for price

Anti-Human TNF alpha

GWB-8F48ED 1 mL Ask for price

Recombinant (E.Coli) purified human Tumor Necrosis Factor-Alpha Variant (TNF-alpha variant, 151-aa), biologically active

TNFA16-R-10 10 ug
EUR 270

Human HE2 alpha Control/blocking peptide #1

HE2A11-P 100 ug
EUR 196.8

Human p73 alpha Control/blocking peptide #2

P73A12-P 100 ug
EUR 196.8

Sheep Anti-Human alpha 1 antichymotrypsin (ACT) IgG, aff pure

ACT11-A 100 ug
EUR 489.6

Rabbit Anti-Human GABAa Receptor alpha 1 (GAA1) Antiserum #1

GAA11-S 100 ul
EUR 548.4

Monoclonal anti-human Lutenizing Hormone Alpha (LH-Alpha) IgG, clone 2 aff pure

LHA12-M 1 mg
EUR 343.2

Goat Anti-Human Alpha 1-Antitrypsin (A1AT) IgG, HRP conjugate

A1AT11-HRP 100 ul
EUR 489.6

Recombinant (E.Coli) Human Casein Kinase 2 alpha

RP-666 3 ug
EUR 708

Recombinant (Sf9) Human Protein Kinase C alpha

RP-676 10 ug
EUR 343.2

Goat Anti-Human IgA (alpha chain sp.) IgG-Biotin Conjugate

10040 0.5 mg
EUR 242.4

Goat Anti-Ferret IgA (alpha), unlabeled

70519 0.5 mg
EUR 255.6

Goat Anti-Human Alpha 1-Antitrypsin (A1AT) IgG, Biotin conjugate

A1AT11-BT 100 ul
EUR 489.6

Purified Human alpha 1 antichymotrypsin (ACT) protein control for WB

ACT11-C 100 ul
EUR 343.2

Monoclonal Anti-Human alpha 1 antichymotrypsin (ACT) IgG, aff pure

ACT12-M 100 ug
EUR 578.4

Rabbit Anti-Human Core-binding factor alpha (CBFA1) antiserum #1

CBFA11-S 100 ul
EUR 548.4

Recombinant (E.Coli) Human Retinoid X Receptor Alpha

RP-1588 10 ug
EUR 270

Rabbit Anti-Rat Glutathione Transferase alpha (GST-alpha) antiserum

GSTA11-S 100 ul
EUR 548.4

Rabbit Anti-Human GABAa Receptor alpha 1 (166-269aa) IgG #1, aff pure

GAA14-A 100 ug
EUR 578.4
  • A central query in most cancers biology is, which cells could be reworked to type tumors? Recent research elucidated the presence of most cancers stem cells which have the unique means to regenerate tumors.

 

  • These most cancers stem cells share many traits with regular stem cells, together with self-renewal and differentiation. With the rising proof that most cancers stem cells exist in a big range of tumors, it’s changing into more and more essential to grasp the molecular mechanisms that regulate self-renewal and differentiation as a result of corruption of genes concerned in these pathways seemingly participates in tumor development.

 

  • This new paradigm of oncogenesis has been validated in a rising record of tumors. Studies of regular and most cancers stem cells from the identical tissue have make clear the ontogeny of tumors.

 

  • That signaling pathways equivalent to Bmi1 and Wnt have related results in regular and most cancers stem cell self-renewal means that widespread molecular pathways regulate each populations. Understanding the biology of most cancers stem cells will contribute to the identification of molecular targets essential for future therapies.

Toward an understanding of NKT cell biology: progress and paradoxes.

  1. Natural killer T (NKT) cells represent a conserved T cell sublineage with distinctive properties, together with reactivity for a artificial glycolipid introduced by CD1d, expression of an invariant T cell antigen receptor (TCR) alpha chain, and weird necessities for thymic choice.
  2. They quickly produce many cytokines after stimulation and thus affect various immune responses and pathogenic processes. Because of intensive analysis effort, now we have realized a lot about elements selling the growth and survival of NKT cells, regulation of their cytokine manufacturing, and the means by which they affect dendritic cells and different cell sorts.

13 mm Diameter Tapped Titanium Tip

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13 mm Diameter Solid Titanium Tip

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19 mm Diameter Tapped Titanium Tip

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19 mm Diameter Solid Titanium Tip

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25 mm Diameter Tapped Titanium Tip

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25 mm Diameter Solid Titanium Tip

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Flat Replaceable Tips 13 mm Diameter Flat Titanium Tip

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Description: use with corresponding Tapped Tips and Tapped Extender Tips

Flat Replaceable Tips 19 mm Diameter Flat Titanium Tip

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Description: use with corresponding Tapped Tips and Tapped Extender Tips

Flat Replaceable Tips 25 mm Diameter Flat Titanium Tip

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Description: use with corresponding Tapped Tips and Tapped Extender Tips

Titanium Cup Tip, 250 ml

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Description: includes Interface Washers

Microtube Tray, 8 Position (for 250 ml Cup Tip)

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Description: includes Interface Washers

Continuous Flow Chamber

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Description: includes Interface Washers

Interface Washers 1.5” Diameter, 5/Pkg

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13 mm Diameter Solid Titanium Extender Tip

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13 mm Diameter Tapped Titanium Extender Tip

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19 mm Diameter Solid Titanium Extender Tip

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19 mm Diameter Tapped Titanium Extender Tip

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25 mm Diameter Solid Titanium Extender Tip

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25 mm Diameter Tapped Titanium Extender Tip

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KoldPod, 1.5ml Micro Tube

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Description: Thermo conductive tube pods

KoldPod, 15ml Conical Tube

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Description: Thermo conductive tube pods

KoldPod, 50ml Conical Tube

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Description: Thermo conductive tube pods

Model 150 V/T Ultrasonic Homogenizer

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Description: Delivers up to 150 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample processing processing.

Model 300 V/T Ultrasonic Homogenizer

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Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip. The Timer and Duty Cycle function increase preciosion in sample.

SONABOZ Sound Abating Chamber

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Description: Reduces cavitational sound emitted during processing.

Model 3000 Ultrasonic Homogenizer

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Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip and includes an intergrated Sound Abating Chmaber to reduce cavitational sound emitted during processing. The Timer and Duty Cycle function increase preciosion in sample.

Model 3000MP Ultrasonic Homogenizer

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Description: Delivers up to 300 Watts of ultrasonic power to the Titanium Tip with preciosion control from a microprocessor and a graphical user interface displayed on a large (145 mm) LCD display. The integrated Sound Abating Chamber reduces cavitational sound emitted during processing.

OMNICON® Zone Reader, 210-240V/50-60Hz

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Description: Designed to Perform multi-plate Assays on round 90/100mm Petri Dishes. The integrated LED illumination system provides transmitted light for brightfield and darkfield illumination of transparent media.

OMNI-Noculator Peni Cylinder Filler, 210-240V/50-60Hz

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Description: A robotic liquid handling system designed to dispense Peni Cylinders and fill Peni Cylinders with the corresponding antibiotic liquid sample.

Peni Cylinder Dispenser with Manual Hopper

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Description: Dispenser can be configured to dispense 4 or 6 Peni Cylinders onto a petri dish.

Peni Cylinder Dispenser with Motorized Hopper, 100-240V/50-60Hz

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Description: The motorized hopper can be configured to dispense 4 or 6 Peni Cylinders onto a petri Dispenser can be disassembled for disinfection.

Stainless Steel Peni Cylinder with Flat Face

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Description: sold in packages of 100 pieces

Stainless Steel Peni Cylinder with Chamfered Face

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Description: sold in packages of 100 pieces

Custom development of ELISAs for other species or antibody isotypes not listed in the catalog. Custom testing of samples for IgG/IgM/IgA or total (IgG+IgM+IgA)

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Alpha-Bungarotoxin, CF®405S, 500 ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-bungarotoxin, CF405s

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Description: Minimum order quantity: 1 unit of 500uG

Alpha-Bungarotoxin, CF®405S, 500 ug

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Alpha-Bungarotoxin, CF®405S 100ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®680R, 500 ug

9-00003
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®680R, 500 ug

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Alpha-Bungarotoxin, CF®680R 100ug

9-00003
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®640R, 500 ug

9-00004
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®640R, 500 ug

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Alpha-Bungarotoxin, CF®640R 100ug

9-00004
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®488A, 500 ug

9-00005
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®488A, 500 ug

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Alpha-Bungarotoxin CF®488A 100ug

9-00005
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®568, 500 ug

9-00006
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®568, 500 ug

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Alpha-Bungarotoxin, CF®568 100ug

9-00006
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®594, 500 ug

9-00007
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®594, 500 ug

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Alpha-Bungarotoxin CF®594 100ug

9-00007
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®633, 500 ug

9-00009
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®633, 500 ug

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Alpha-Bungarotoxin, CF®633 100ug

9-00009
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

SARS-CoV-2 Indicator Cell Line for RNA Replication - GFP Reporter only

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Description: SARS-CoV-2 GFP reporter cell line using HEK293T (ACE2/TMPRSS2) cells

Alpha-Bungarotoxin, 1 mg

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, 1 mg

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Fluorescein-Alpha-Bungarotoxin, 500 ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Fluorescein-Alpha-Bungarotoxin, 500 ug

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Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Tetramethylrhodamine-Alpha-Bungarotoxin, 500 ug

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Fluorescein-alpha-bungarotoxin, 10x50ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Fluorescein-alpha-bungarotoxin, 10x50ug

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Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Tetramethylrhodamine-A-Bungarotoxin, 10x50 ug

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Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Sulforhodamine 101-Alpha-Bungarotoxin, 500 ug

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Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Sulforhodamine 101-Alpha-Bungarotoxin, 50 ug

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Biotin-XX-A-Bungarotoxin, 500 ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Biotin-XX-A-Bungarotoxin, 500 ug

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Alpha-Bungarotoxin, CF®555, 500 ug

9-00018
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®555, 500 ug

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Alpha-Bungarotoxin, CF®555 100ug

9-00018
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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Acrylamide, Chemzymes Ultra Pure®

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Description: 79-06-1

Acrylamide, Chemzymes Ultra Pure®

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Description: 79-06-1

Biotin-cAMP, 1 mg

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Description: N/A

Biotin-cAMP, 1 mg

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Description: N/A

Biotin-cAMP, 50 ug

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Biotin-cGMP, 1 mg

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Description: N/A

Biotin-cGMP, 1 mg

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Description: N/A

Biotin-cGMP, 20x50 ug

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Cyanine 644-cAMP, 1 mg

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Description: N/A

Cyanine 644-cAMP, 1 mg

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Description: N/A

Cyanine 644-cAMP, 20x50 ug

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Fluorescein Methotrexate, Triammonium Salt, 1 mg

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Description: N/A

Fluorescein Methotrexate, Triammonium Salt, 1 mg

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Staurosporine

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Description: N/A

Staurosporine

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Alpha-Bungarotoxin, CF®543, 500 ug

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Description: Alpha-bungarotoxin from Krait snake venom (Bungarus multicinctus)

Alpha-Bungarotoxin, CF®543, 500 ug

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  1. Despite this progress, data of the pure antigen(s) they acknowledge and their physiologic position stay incomplete. The activation of NKT cells paradoxically can lead both to suppression or stimulation of immune responses, and we can’t predict which can happen. Despite this uncertainty, many investigators are hopeful that immune therapies could be developed based mostly on NKT cell stimulation.
  2. The discovery of mouse embryonic stem (ES) cells >20 years in the past represented a main advance in biology and experimental drugs, because it enabled the routine manipulation of the mouse genome.
  3. Along with the capability to induce genetic modifications, ES cells offered the foundation for establishing an in vitro mannequin of early mammalian growth and represented a putative new supply of differentiated cell sorts for cell alternative remedy.
  4. While ES cells have been used extensively for creating mouse mutants for greater than a decade, their software as a mannequin for developmental biology has been restricted and their use in cell alternative remedy stays a purpose for a lot of in the subject.
  5. Recent advances in our understanding of ES cell differentiation, detailed in this evaluation, have offered new insights important for establishing ES cell-based developmental fashions and for the technology of clinically related populations for cell remedy.

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